Palatrigine

Effect of omapatrilat on myocardium TNF-α、MMP-2 expression and ventricular remodeling (after) myocardial infarction in rats;

奥帕曲拉对大鼠心肌梗死后肿瘤坏死因子-α、基质金属蛋白酶-2的表达及心室重构的影响

Aim:To investigate the effects of omapatrilat(OMA) on endothelin-1-induced proliferation of cardiac fibroblasts(CFs).

目的:探讨奥帕曲拉(omapatrilat,OMA)对内皮素-1(ET-1)诱导的心脏成纤维细胞(CFs)增殖的干预作用及可能机制。